THUILLIER Raphaël

Publications HAL

Article dans une revue (77 documents)

Perrine Burdeyron, Sébastien Giraud, Maryne Lepoittevin, Nina Jordan, Sonia Brishoual, et al.. Dynamic conditioning of porcine kidney grafts with extracellular vesicles derived from urine progenitor cells: A proof‐of‐concept study. Clinical and Translational Medicine, 2024, 14 (12), ⟨10.1002/ctm2.70095⟩. ⟨hal-05079026⟩
Maryne Lepoittevin, Quentin Blancart-Remaury, Nicolas Lévêque, Arnaud Thille, Thomas Brunet, et al.. Advantages of Metabolomics-Based Multivariate Machine Learning to Predict Disease Severity: Example of COVID. International Journal of Molecular Sciences, 2024, 25 (22), pp.12199. ⟨10.3390/ijms252212199⟩. ⟨hal-04831902⟩
Estelle Blochouse, Rony Eid, Nahla Araji, Wei Tuo, Rémi Châtre, et al.. VOC-Based Probes, a New Set of Analytical Tools to Monitor Patient Health from Blood Sample. Proof of Concept on Tracking COVID-19 Infection. Analytical Chemistry, 2023, 95 (31), pp.11572-11577. ⟨10.1021/acs.analchem.3c01732⟩. ⟨hal-04508245⟩
Maryne Lepoittevin, Quentin Blancart-Remaury, Thomas Kerforne, Luc Pellerin, Thierry Hauet, et al.. Comparison between 5 extractions methods in either plasma or serum to determine the optimal extraction and matrix combination for human metabolomics. Cellular and Molecular Biology Letters, 2023, 28 (1), pp.43. ⟨10.1186/s11658-023-00452-x⟩. ⟨hal-04249335⟩
Nicolas Melis, Isabelle Rubera, Sebastien Giraud, Marc Cougnon, Christophe Duranton, et al.. Renal Ischemia Tolerance Mediated by eIF5A Hypusination Inhibition Is Regulated by a Specific Modulation of the Endoplasmic Reticulum Stress. Cells, 2023, 12 (3), pp.409. ⟨10.3390/cells12030409⟩. ⟨hal-03957746⟩
Raphael Thuillier. Molecular Frontiers in Transplantation-Induced Ischemia–Reperfusion Injury. International Journal of Molecular Sciences, 2023, 24 (4), pp.3450. ⟨10.3390/ijms24043450⟩. ⟨hal-04249519⟩
Raphaël Thuillier, Marine Coué, Lionel Badet. Organ conservation and transportation modalities. Revue du Praticien (La), 2023. ⟨hal-05099436⟩
Maryne Lepoittevin, Sébastien Giraud, Thomas Kerforne, Géraldine Allain, Raphaël Thuillier, et al.. How to improve results after DCD (donation after circulation death). La Presse Médicale, 2022, 51 (4), pp.104143. ⟨10.1016/j.lpm.2022.104143⟩. ⟨hal-05097897⟩
Valentin Bossard, Nicolas Bourmeyster, Sophie Pasini, Pierre Dupuis, Souleiman El Balkhi, et al.. Problematic rise of vitamin B6 supplementation overuse and potential risk to bariatric surgery patients. Nutrition, 2022, 102, pp.111738. ⟨10.1016/j.nut.2022.111738⟩. ⟨hal-05097899⟩
Maryne Lepoittevin, Thomas Kerforne, Luc Pellerin, Thierry Hauet, Raphaël Thuillier. Molecular Markers of Kidney Transplantation Outcome: Current Omics Tools and Future Developments. International Journal of Molecular Sciences, 2022, 23 (11), pp.6318. ⟨10.3390/ijms23116318⟩. ⟨hal-05097900⟩
Maryne Lepoittevin, Sébastien Giraud, Thomas Kerforne, Benoit Barrou, Lionel Badet, et al.. Preservation of Organs to Be Transplanted: An Essential Step in the Transplant Process. International Journal of Molecular Sciences, 2022, 23 (9), pp.4989. ⟨10.3390/ijms23094989⟩. ⟨hal-04522310⟩
Pauline Chazelas, Clara Steichen, Frédéric Favreau, Patrick Trouillas, Patrick Hannaert, et al.. Oxidative Stress Evaluation in Ischemia Reperfusion Models: Characteristics, Limits and Perspectives. International Journal of Molecular Sciences, 2021, 22 (5), pp.2366. ⟨10.3390/ijms22052366⟩. ⟨hal-03224524⟩
Ophélie Pasini-Chabot, Julia Vincent, Sylvain Le Pape, Maryne Lepoittevin, Wassim Kaaki, et al.. High throughput proteomic exploration of hypothermic preservation reveals active processes within the cell associated with cold ischemia kinetic. International Journal of Molecular Sciences, 2021, 22 (5), pp.1-26. ⟨10.3390/ijms22052384⟩. ⟨hal-03313190⟩
Jérôme Danion, Raphaël Thuillier, Géraldine Allain, Patrick Bruneval, Jacques Tomasi, et al.. Evaluation of Liver Quality after Circulatory Death versus Brain Death: A Comparative Preclinical Pig Model Study. International Journal of Molecular Sciences, 2020, 21 (23), pp.9040. ⟨10.3390/ijms21239040⟩. ⟨hal-05097903⟩
Sebastien Giraud, Raphael Thuillier, Jérome Cau, Thierry Hauet. In Vitro/Ex Vivo Models for the Study of Ischemia Reperfusion Injury during Kidney Perfusion. International Journal of Molecular Sciences, 2020, 21 (21), pp.8156. ⟨10.3390/ijms21218156⟩. ⟨hal-03102520⟩
Valentin Bossard, Raphaël Thuillier. Donor anti-complement therapy: Complement-ing the protection array?. American Journal of Transplantation, 2020, 20 (6), pp.1473-1474. ⟨10.1111/ajt.15834⟩. ⟨hal-05097904⟩
Louise Alechinsky, Frédéric Favreau, Petra Cechova, Sofiane Inal, Pierre-Antoine Faye, et al.. Tannic Acid Improves Renal Function Recovery after Renal Warm Ischemia–Reperfusion in a Rat Model. Biomolecules, 2020, 10 (3), pp.439. ⟨10.3390/biom10030439⟩. ⟨hal-02513505⟩
David Soussi, Xavier Rod, Raphael Thuillier, Suzanne Leblanc, Jean-Michel Goujon, et al.. Preclinical Modeling of DCD Class III Donation: Paving the Way for the Increased Use of This Challenging Donor Type. BioMed Research International , 2019, 2019, pp.1-9. ⟨10.1155/2019/5924101⟩. ⟨hal-03279411⟩
Jacques Kaminski, Patrick Hannaert, Abdelsalam Kasil, Raphael Thuillier, Elisabeth Leize, et al.. Efficacy of the natural oxygen transporter HEMO 2 life ® in cold preservation in a preclinical porcine model of donation after cardiac death. Transplant International, 2019, 32 (9), pp.985-996. ⟨10.1111/tri.13434⟩. ⟨hal-02346828⟩
Valentin Bossard, Ysé Sauvageon, François Fraissinet, Brigitte Dreyfus, Raphaël Thuillier, et al.. False paraprotein-induced hypoglycemia in the measurement of glucose by the hexokinase method. Annales de Biologie Clinique, 2019, 77 (4), pp.439-445. ⟨10.1684/abc.2019.1465⟩. ⟨hal-05097908⟩
Thomas Kerforne, Sébastien Giraud, Jerome Danion, Raphael Thuillier, Pierre Couturier, et al.. Rapid or slow time to brain death? Impact on kidney graft injuries in an allotransplantation porcine model. International Journal of Molecular Sciences, 2019, 20 (15), pp.3671. ⟨10.3390/ijms20153671⟩. ⟨hal-02270575⟩
Nicolas Melis, Clara Steichen, Sebastien Giraud, Yse Sauvageon, Jacques Kaminski, et al.. Emerging therapeutic strategies for transplantation-induced acute kidney injury: protecting the organelles and the vascular bed. Expert Opinion on Therapeutic Targets, 2019, 23 (6), pp.495-509. ⟨10.1080/14728222.2019.1609451⟩. ⟨hal-02153427⟩
Sébastien Giraud, Clara Steichen, Géraldine Allain, Pierre Couturier, Delphine Labourdette, et al.. Dynamic transcriptomic analysis of ischemic injury in a porcine pre-clinical model mimicking donors deceased after circulatory death. Transplant International, 2019, 32, pp.20. ⟨10.1111/tri.13379⟩. ⟨hal-02154350⟩
Thomas Kerforne, Geraldine Allain, Sébastien Giraud, Delphine Bon, Virginie Ameteau, et al.. Defining the optimal duration for normothermic regional perfusion in the kidney donor: A porcine preclinical study. American Journal of Transplantation, 2019, 19 (3), pp.737-751. ⟨10.1111/ajt.15063⟩. ⟨hal-01948305⟩
David Soussi, Jérôme Danion, Edouard Baulier, Frédéric Favreau, Ysé Sauvageon, et al.. Vectisol formulation enhances solubility of resveratrol and brings its benefits to kidney transplantation in a preclinical porcine model. International Journal of Molecular Sciences, 2019, 20 (9), pp.2268. ⟨10.3390/ijms20092268⟩. ⟨hal-02968028⟩
Raphaël Thuillier, Eric Delpy, Xavier Matillon, Jacques Kaminski, Abdelsalam Kasil, et al.. Preventing acute kidney injury during transplantation: the application of novel oxygen carriers. Expert Opinion on Investigational Drugs, 2019, 28 (7), pp.643-657. ⟨10.1080/13543784.2019.1628217⟩. ⟨hal-02620049⟩
C. Steichen, S. Giraud, D. Bon, B. Barrou, L. Badet, et al.. Barriers and Advances in Kidney Preservation. BioMed Research International , 2018, 2018, pp.1-15. ⟨10.1155/2018/9206257⟩. ⟨hal-02346840⟩
Sylvain Le Pape, Ophélie Pasini-Chabot, Pierre Couturier, Pierre-Olivier Delpech, Romain Volmer, et al.. Decoding cold ischaemia time impact on kidney graft: the kinetics of the unfolded protein response pathways. Artificial Cells, Nanomedicine, and Biotechnology, 2018, 46 (sup3), pp.1 - 13. ⟨10.1080/21691401.2018.1518908⟩. ⟨hal-01913845⟩
Sebastien Giraud, Raphael Thuillier, Ricardo Codas, Emily Manguy, Benoit Barrou, et al.. The Optimal PEG for Kidney Preservation: A Preclinical Porcine Study. International Journal of Molecular Sciences, 2018, 19 (2), pp.454. ⟨10.3390/ijms19020454⟩. ⟨hal-01762477⟩
Raphaël Thuillier, Thierry Hauet. Impact of hypothermia and oxygen deprivation on the cytoskeleton in organ preservation models. BioMed Research International , 2018, 2018, pp.1-10. ⟨10.1155/2018/8926724⟩. ⟨hal-02629132⟩
Sébastien Giraud, Clara Steichen, Geraldine Allain, Pierre Couturier, Delphine Labourdette, et al.. Dynamic transcriptomic analysis of Ischemic Injury in a Porcine Pre-Clinical Model mimicking Donors Deceased after Circulatory Death. Scientific Reports, 2018, 8, pp.5986. ⟨10.1038/s41598-018-24282-6⟩. ⟨hal-01791235⟩
C. Delehouzé, S. Leverrier-Penna, F. Le Cann, A. Comte, M. Jacquard-Fevai, et al.. 6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury. Scientific Reports, 2017, 7 (1), pp.12931. ⟨10.1038/s41598-017-12788-4⟩. ⟨hal-01616456⟩
Thierry Hauet, Raphael Thuillier. Protecting the mitochondria against ischemia reperfusion: A gassy solution?. American Journal of Transplantation, 2017, 17 (2), pp.313-314. ⟨10.1111/ajt.14150⟩. ⟨hal-01594878⟩
Pierre-Olivier Delpech, Raphael Thuillier, Thibault Saintyves, Jerome Danion, Sylvain Le Pape, et al.. Inhibition of complement improves graft outcome in a pig model of kidney autotransplantation. Journal of Translational Medicine, 2016, 14 (1), pp.1-13. ⟨10.1186/s12967-016-1013-7⟩. ⟨hal-01928671⟩
Thomas Kerforne, Frédéric Favreau, Raphaël Thuillier, Thierry Hauet, Michel Pinsard. Vers une personnalisation de la conservation des greffons rénaux ?. Néphrologie & Thérapeutique, 2016, 12 (6), pp.437-442. ⟨10.1016/j.nephro.2016.02.020⟩. ⟨hal-01601902⟩
S. Tillet, Sébastien Giraud, P. Delpech, Raphael Thuillier, V. Ameteau, et al.. Kidney graft outcome using an anti-Xa therapeutic strategy in an experimental model of severe ischaemia-reperfusion injury. British Journal of Surgery, 2015, 102 (1), pp.132 - 142. ⟨10.1002/bjs.9662⟩. ⟨hal-01928106⟩
Sébastien Giraud, Geraldine Allain, Vanessa Mallet, Rémi Coudroy, Nathalie Quellard, et al.. Influence of preservation temperature on endothelial cells and kidney phenotypes. Transplant International, 2015, 28 (S1), pp.16-17. ⟨10.1111/tri.12493⟩. ⟨hal-01244497⟩
Sébastien Giraud, Geraldine Allain, Solenne Tillet, Antoine Thierry, Rémi Coudroy, et al.. Influence of preservation temperature on endothelial cells and kidney phenotypes. Transplant International, 2015, 28, pp.308. ⟨hal-02630173⟩
P. Delpech, R. Thuillier, S. Le Pape, L. Rossard, C. Jayle, et al.. Effects of warm ischaemia combined with cold preservation on the hypoxia-inducible factor 1α pathway in an experimental renal autotransplantation model. British Journal of Surgery, 2014, 101 (13), pp.1739 - 1750. ⟨10.1002/bjs.9611⟩. ⟨hal-01928078⟩
Sylvain Le Pape, Elena Dimitrova, Patrick Hannaert, Alexander Konovalov, Romain Volmer, et al.. Polynomial algebra reveals diverging roles of the unfolded protein response in endothelial cells during ischemia-reperfusion injury. FEBS Letters, 2014, 588 (17), pp.3062 - 3067. ⟨10.1016/j.febslet.2014.05.065⟩. ⟨hal-01928041⟩
R. Thuret, T. Saint Yves, X. Tillou, N. Chatauret, R. Thuillier, et al.. Ischemic pre- and post-conditioning : current clinical applications. Progrès en Urologie, 2014, 24, pp.S56 - S61. ⟨10.1016/S1166-7087(14)70065-X⟩. ⟨hal-01930321⟩
T. Saint Yves, S. Giraud, P.-O. Delpech, R. Thuillier, T. Hauet. Additives to preservation solutions. Progrès en Urologie, 2014, 24, pp.S31 - S36. ⟨10.1016/S1166-7087(14)70061-2⟩. ⟨hal-01930329⟩
R. Thuillier, G. Allain, Sebastien Giraud, T. Saintyves, P. Delpech, et al.. Cyclodextrin Curcumin Formulation Improves Outcome in a Preclinical Pig Model of Marginal Kidney Transplantation. American Journal of Transplantation, 2014, 14 (5), pp.1073 - 1083. ⟨10.1111/ajt.12661⟩. ⟨hal-01925025⟩
Delphine Bon, Claire Billault, Raphaël Thuillier, William Hebrard, Nadège Boildieu, et al.. Analysis of perfusates during hypothermic machine perfusion by NMR spectroscopy: a potential tool for predicting kidney graft outcome.. Transplantation, 2014, 97 (8), pp.810-6. ⟨10.1097/TP.0000000000000046⟩. ⟨inserm-01057477⟩
Raphaël Thuillier, Geraldine Allain, Olivier Celhay, William Hebrard, Benoit Barrou, et al.. Benefits of active oxygenation during hypothermic machine perfusion of kidneys in a preclinical model of deceased after cardiac death donors.. Journal of Surgical Research, 2013, 184 (2), pp.1174-81. ⟨10.1016/j.jss.2013.04.071⟩. ⟨inserm-00871250⟩
Ludivine Rossard, Frédéric Favreau, Sebastien Giraud, Raphael Thuillier, Sylvain Le Pape, et al.. Role of warm ischemia on innate and adaptive responses in a preclinical renal auto-transplanted porcine model.. Journal of Translational Medicine, 2013, 11 (1), pp.129. ⟨10.1186/1479-5876-11-129⟩. ⟨inserm-00827220⟩
Frédéric Favreau, Sébastien Giraud, Delphine Bon, Nicolas Chatauret, Raphaël Thuillier, et al.. L’ischémie reperfusion : Acteur essentiel du devenir du greffon rénal. Médecine/Sciences, 2013, 29 (2), pp.183-8. ⟨10.1051/medsci/2013292016⟩. ⟨inserm-00871213⟩
Delphine Bon, Nicolas Chatauret, Sébastien Giraud, Raphael Thuillier, Frédéric Favreau, et al.. New strategies to optimize kidney recovery and preservation in transplantation.. Nature Reviews Nephrology, 2012, 8 (6), pp.339-47. ⟨10.1038/nrneph.2012.83⟩. ⟨inserm-00871237⟩
G. Manku, Y. Wang, Raphaël Thuillier, C. Rhodes, M. Culty. Developmental Expression of the Translocator Protein 18 kDa (TSPO) in Testicular Germ Cells. Current Molecular Medicine, 2012, 12 (4), pp.467-475. ⟨10.2174/156652412800163389⟩. ⟨hal-05099468⟩
L. Rossard, F. Favreau, Julie Demars, R. Robert, C. Nadeau, et al.. Evaluation of Early Regenerative Processes in a Preclinical Pig Model of Acute Kidney Injury. Current Molecular Medicine, 2012, 12 (4), pp.502 - 505. ⟨10.2174/1566524011207040502⟩. ⟨hal-02642711⟩
R. Thuillier, T. Hauet. Role of Translocator Protein in Renal Ischemia Reperfusion, Renal Preservation and Acute Kidney Injury. Current Molecular Medicine, 2012, 12 (4), pp.413 - 425. ⟨10.2174/156652412800163433⟩. ⟨hal-02649562⟩
Sébastien Giraud, Delphine Bon, Yann Neuzillet, Raphael Thuillier, Michel Eugene, et al.. Concentration and chain length of polyethylene glycol in islet isolation solution: evaluation in a pancreatic islet transplantation model.. Cell Transplantation, 2012, 21 (9), pp.2079-88. ⟨10.3727/096368912X638928⟩. ⟨inserm-00871259⟩
Raphael Thuillier, Ricardo Codas, Etienne Marchand, Hubert Lathelize, Olivier Page, et al.. Chronic renoprotective effect of pulsatile perfusion machine RM3 and IGL-1 solution in a preclinical kidney transplantation model. Journal of Translational Medicine, 2012, 10 (1), pp.233. ⟨10.1186/1479-5876-10-233⟩. ⟨inserm-00773201⟩
R. Thuillier, D. Dutheil, M. T. N. Trieu, V. Mallet, G. Allain, et al.. Supplementation With a New Therapeutic Oxygen Carrier Reduces Chronic Fibrosis and Organ Dysfunction in Kidney Static Preservation. American Journal of Transplantation, 2011, 11 (9), pp.1845-1860. ⟨10.1111/j.1600-6143.2011.03614.x⟩. ⟨hal-01250926⟩
Ricardo Codas, Raphaël Thuillier, Thierry Hauet, Lionel Badet. Renoprotective effect of pulsatile perfusion machine RM3: pathophysiological and kidney injury biomarker characterization in a preclinical model of autotransplanted pig. BJU International, 2011, 109 (1), pp.141-147. ⟨10.1111/j.1464-410X.2011.10393.x⟩. ⟨hal-05097913⟩
Thibault Desurmont, Sébastien Giraud, Jerome Cau, Jean-Michel Goujon, Michel Scepi, et al.. Trophic Factor and FR167653 Supplementation During Cold Storage Rescue Chronic Renal Injury. Journal of Urology, 2011, 185 (3), pp.1139 - 1146. ⟨10.1016/j.juro.2010.10.032⟩. ⟨hal-02645427⟩
S. Giraud, Florence Favreau, N. Chatauret, R. Thuillier, S. Maiga, et al.. Contribution of Large Pig for Renal Ischemia-Reperfusion and Transplantation Studies: The Preclinical Model. Journal of Biomedicine and Biotechnology, 2011, pp.1-14. ⟨10.1155/2011/532127⟩. ⟨hal-02650499⟩
Nicolas Chatauret, Raphaël Thuillier, Thierry Hauet. Preservation strategies to reduce ischemic injury in kidney transplantation: pharmacological and genetic approaches. Current Opinion in Organ Transplantation, 2011, 16 (2), pp.180 - 187. ⟨10.1097/MOT.0b013e3283446b1d⟩. ⟨hal-02644083⟩
R. Thuillier, Christine Renard, Claire Gaillard, Julie Demars, Denis Milan, et al.. Effect of polyethylene glycol-based preservation solutions on graft injury in experimental kidney transplantation. British Journal of Surgery, 2011, 98 (3), pp.368-378. ⟨10.1002/bjs.7332⟩. ⟨hal-01211937⟩
Thierry Hauet, Raphaël Thuillier, Jean Paul Tillement. Ischemia reperfusion : an unavoidable phase of transplant procedures. Bulletin de l'Académie Nationale de Médecine, 2011, 195 (4-5), pp.831 - 842. ⟨10.1016/s0001-4079(19)32037-0⟩. ⟨hal-02645229⟩
Raphaël Thuillier, Sébastien Giraud, Frédéric Favreau, Jean-Michel Goujon, Thibault Desurmont, et al.. Improving Long-Term Outcome in Allograft Transplantation: Role of Ionic Composition and Polyethylene Glycol. Transplantation, 2011, 91 (6), pp.605 - 614. ⟨10.1097/TP.0b013e3182090fa3⟩. ⟨hal-02642580⟩
Nader Vaziri, Raphaël Thuillier, Frederic Favreau, Michel Eugene, Serge Milin, et al.. Analysis of machine perfusion benefits in kidney grafts: a preclinical study. Journal of Translational Medicine, 2011, 9 (1), pp.15. ⟨10.1186/1479-5876-9-15⟩. ⟨inserm-00663684⟩
Raphaël Thuillier, Monty Mazer, Gurpreet Manku, Annie Boisvert, Yan Wang, et al.. Interdependence of Platelet-Derived Growth Factor and Estrogen-Signaling Pathways in Inducing Neonatal Rat Testicular Gonocytes Proliferation1. Biology of Reproduction, 2010, 82 (5), pp.825-836. ⟨10.1095/biolreprod.109.081729⟩. ⟨hal-05097919⟩
F. Favreau, R. Thuillier, J. Caub, S. Milin, E. Manguy, et al.. Anti-thrombin therapy during warm ischemia and cold preservation prevents chronic kidney graft fibrosis in a DCD model. American Journal of Transplantation, 2010, 10 (1), pp.30-39. ⟨10.1111/j.1600-6143.2009.02924.x⟩. ⟨hal-02667085⟩
Raphaël Thuillier, Frédéric Favreau, Olivier Celhay, Laurent Macchi, Serge Milin, et al.. Thrombin inhibition during kidney ischemia-reperfusion reduces chronic graft inflammation and tubular atrophy. Transplantation, 2010, 90 (6), pp.612 - 621. ⟨10.1097/TP.0b013e3181d72117⟩. ⟨hal-02668877⟩
Raphaël Thuillier, Gurpreet Manku, Yan Wang, Martine Culty. Changes in MAPK pathway in neonatal and adult testis following fetal estrogen exposure and effects on rat testicular cells. Microscopy Research and Technique, 2009, 72 (11), pp.773-786. ⟨10.1002/jemt.20756⟩. ⟨hal-05097925⟩
Raphaël Thuillier, Jean Tillement, Thierry Hauet. Renal Protective Effect of Metabolic Therapy in Patients with Coronary Artery Disease and Diabetes: From Bench to Bed Side. Current Pharmaceutical Design, 2009, 15 (8), pp.863-882. ⟨10.2174/138161209787582110⟩. ⟨hal-05097894⟩
J. Cau, R. Thuillier, A. van Der Plaats, William Hebrard, H. Leuvenink, et al.. Hypothermic machine perfusion of DCD kydneys: the role of oxygen in recovery from IR-injury.. Transplant International, 2009, 22 (Suppl. 2), pp.257-258. ⟨hal-02654843⟩
Sébastien Giraud, Raphaël Thuillier, Aude Belliard, William Hebrard, Cédric Nadeau, et al.. Direct Thrombin Inhibitor Prevents Delayed Graft Function in a Porcine Model of Renal Transplantation. Transplantation, 2009, 87 (11), pp.1636-1644. ⟨10.1097/TP.0b013e3181a5b154⟩. ⟨hal-02662887⟩
R. Codas, L. Badet, M. Eugene, S. Giraud, R. Thuillier, et al.. Evaluation of pulsatile perfusion machine RM3 for kidney preservation in a swine model of renal autotransplantation. Transplantation Proceedings, 2009, 41 (8), pp.3296-3298. ⟨10.1016/j.transproceed.2009.08.045⟩. ⟨hal-02668611⟩
Frédéric Favreau, Ludivine Rossard, Keqiang Zhang, Thibault Desurmont, Emilie Manguy, et al.. Expression and modulation of translocator protein and its partners by hypoxia reoxygenation or ischemia and reperfusion in porcine renal models. American Journal of Physiology. Renal Physiology, 2009, 297 (1), pp.F177-F190. ⟨10.1152/ajprenal.90422.2008⟩. ⟨hal-02661468⟩
C. Jayle, J.P. Faure, R. Thuillier, J.M. Goujon, J.P. Richer, et al.. Influence of nephron mass and a phosphorylated 38 mitogen-activated protein kinase inhibitor on the development of early and long-term injury after renal warm ischaemia. British Journal of Surgery, 2009, 96 (7), pp.799-808. ⟨10.1002/bjs.6589⟩. ⟨hal-02661606⟩
Martine Culty, Raphaël Thuillier, Wenping Li, Yan Wang, Daniel Martinez-Arguelles, et al.. In Utero Exposure to Di-(2-ethylhexyl) Phthalate Exerts Both Short-Term and Long-Lasting Suppressive Effects on Testosterone Production in the Rat1. Biology of Reproduction, 2008, 78 (6), pp.1018-1028. ⟨10.1095/biolreprod.107.065649⟩. ⟨hal-05097927⟩
Raphaël Thuillier. Interleukin-13 Mediates Proliferation of Renal Tubular Epithelium Leading to Kidney Allograft Fibrosis. Journal of Epithelial Biology Pharmacology, 2008. ⟨hal-05099464⟩
O. Cheng, Raphaël Thuillier, E. Sampson, G. Schultz, P. Ruiz, et al.. Connective Tissue Growth Factor is a Biomarker and Mediator of Kidney Allograft Fibrosis. American Journal of Transplantation, 2006, 6 (10), pp.2292-2306. ⟨10.1111/j.1600-6143.2006.01493.x⟩. ⟨hal-05097916⟩
Yan Wang, Raphaël Thuillier, Martine Culty. Prenatal Estrogen Exposure Differentially Affects Estrogen Receptor-Associated Proteins in Rat Testis Gonocytes1. Biology of Reproduction, 2004, 71 (5), pp.1652-1664. ⟨10.1095/biolreprod.104.030205⟩. ⟨hal-05097929⟩
Raphaël Thuillier, Yan Wang, Martine Culty. Prenatal Exposure to Estrogenic Compounds Alters the Expression Pattern of Platelet-Derived Growth Factor Receptors α and β in Neonatal Rat Testis: Identification of Gonocytes as Targets of Estrogen Exposure1. Biology of Reproduction, 2003, 68 (3), pp.867-880. ⟨10.1095/biolreprod.102.009605⟩. ⟨hal-05097930⟩

Communication dans un congrès (57 documents)

Raphaël Thuillier. Supplémentation Vitaminique et Risque de Surcharge suite à la Chirurgie Bariatrique: Cas de la Vitamine B6. symposium conjoint de la SFVB (Société Française Vitamines et Biofacteurs) et la SFERETE (Société Francophone d'Etude et de Recherche sur les Eléments Toxiques et Essentiels, 2023, Marseille, France. ⟨hal-05099555⟩
Raphaël Thuillier. La mitochondrie au cœur de la préservation : a-t-elle les reins assez solides pour ne pas s'époumoner ?. Club de la Transplantation, 2018, Lilles, France. ⟨hal-05099553⟩
Raphaël Thuillier. Endothelial glycocallix and its role in IRI. International Meeting on Ischemia Reperfusion in Transplantation, 2018, Poitiers, France. ⟨hal-05099544⟩
Raphaël Thuillier. Les cibles de la néphroprotection contre les lésions d’ischémie reperfusion. WE du Réseau des Infarctus de Reperfusion, 2017, Nazelles-Negron, France. ⟨hal-05099545⟩
Raphaël Thuillier. Mitochondria : target and key player during Ischemia Reperfusion in Organ Transplantation. IHU Liryc, 2017, Bordeaux, France. ⟨hal-05099549⟩
Souleymane Maïga, Tackwa Khalifeh, Antoine Thierry, Franck Guy, Jerome Cau, et al.. High-fat diet promotes early vascular remodeling in a renal porcine auto-transplantation model. 17. Congress of the European Society for Organ Transplantation, European Society for Organ Transplantation (ESOT). INT., Sep 2015, Bruxelles, Belgium. 1 p. ⟨hal-02744213⟩
Sebastien Giraud, Raphael Thuillier, Sophie Lamarre, Solenne Tillet, Michel Eugene, et al.. High throughput proteomic exploration of cold ischemia mechanisms. 17. Congress of the European Society for Organ Transplantation, European Society for Organ Transplantation (ESOT). INT., Sep 2015, Bruxelles, Belgium. 1 p. ⟨hal-01886367⟩
Raphaël Thuillier, Thierry Hauet. Fate and role of the cytoskeletton during cold ischemia. 17. Congress of the European Society for Organ Transplantation, European Society for Organ Transplantation (ESOT). INT., Sep 2015, Bruxelles, Belgium. 1 p. ⟨hal-02740330⟩
Sylvain Lepape, Raphaël Thuillier, Thierry Hauet. Influence of the endoplasmic reticulum in cell survival during cold ischemia. 17. Congress of the European Society for Organ Transplantation, European Society for Organ Transplantation (ESOT). INT., Sep 2015, Bruxelles, Belgium. 1 p. ⟨hal-02740331⟩
Vivien Aubert, Francois Guillaud, Thierry Hauet, Patrick Hannaert, Raphaël Thuillier. Cell atp and viability alterations induced by ischemia-reperfusion in the renal cortex: an agent-based computer model. 17. Congress of the European Society for Organ Transplantation, European Society for Organ Transplantation (ESOT). INT., Sep 2015, Bruxelles, Belgium. 1 p. ⟨hal-02740333⟩
Sébastien Giraud, Solenne Tillet, Thibault Saintyves, Virginie Ameteau, Sandrine Joffrion, et al.. Inhibition of coagulation proteases xa and iia on ischemia reperfusion injuries in renal transplantation model. 17. Congress of the European Society for Organ Transplantation, European Society for Organ Transplantation (ESOT). INT., Sep 2015, Bruxelles, Belgium. 1 p. ⟨hal-02743470⟩
Raphaël Thuillier. Fate and role of the cytoskeletton during cold ischemia. Congress of the European Society for Organ Transplantation, European Society for Organ Transplantation, 2015, Brussel, Belgium. ⟨hal-05099358⟩
Raphaël Thuillier. Reperfusion-Induced Immune Response and Improves Kidney Graft Outcome. The World Transplant Congress, 2014, San franscisco, CA, United States. ⟨hal-05099352⟩
Raphaël Thuillier. Determination of Ischemia Reperfusion Mechanisms at the Cellular Level: the Unfolded Protein Response. The World Transplant Congress, 2014, San francisco, United States. ⟨hal-05099432⟩
Ophélie Pasini-Chabot, Julia Vincent, Sylvain Le Pape, Wassim Kaaki, Jean-Baptiste Woillard, et al.. High throughput Proteomic Exploration of Hypothermic Preservation reveals Dynamic Processes within the Cell interconnected to Cold Ischemia Time. 14th World Congress of the International-Pancreas-and-Islet-Transplant-Association (IPITA), Sep 2013, Monterey (Californie), United States. pp.1, ⟨10.1097/01.tp.0000543683.05650.23⟩. ⟨hal-02734673⟩
David Soussi, Xavier Rod, Thomas Kerforne, Raphaël Thuillier, Benoit Barrou, et al.. Preclinical Modeling of DCD class III Donation and Evaluation of the Most Adapted Preservation Protocol: Paving the Way for the Increased Use of this Challenging Donor Type. 14th World Congress of the International-Pancreas-and-Islet-Transplant-Association (IPITA) 27th International Congress of the Transplantation-Society (TTS), Sep 2013, Madrid, Spain. pp.1, ⟨10.1097/01.tp.0000543823.93493.ce⟩. ⟨hal-02737875⟩
Raphaël Thuillier. Influence du stress du réticulum endoplasmique sur la survie cellulaire pendant l’ischémie froide. Congrès de l’ANPMCB, 2013, Poitiers, France. ⟨hal-05099346⟩
Raphaël Thuillier. Recombinant C1 inhibitor limits ischemia reperfusion injury and improves graft outcomes.. European Society Of Transplantation Congress, 2013, Vienna (Austria), Austria. ⟨hal-05099430⟩
Solenne Tillet, Sébastien Guiraud, William Hebrard, Raphaël Thuillier, Gérard Mauco, et al.. New anticoagulant improves early and long term kidney graft function. 12. Annual congress of the French Speaking Society of Transplantation, French Speaking Society of Transplantation. FRA., Dec 2012, Nantes, France. ⟨10.1111/tri.12030⟩. ⟨hal-02746975⟩
R. Codas, R. Thuillier, P. O. Delpech, B. Barrou, L. Badet, et al.. The final showdown: preclinical comparison between perfusion machines ORS Lifeport and Waters RM3. 1. International Meeting on Ischemia Reperfusion Injuries in Transplantation (IMIRT), May 2012, Poitiers, France. ⟨hal-02749517⟩
S. Tillet, S. Giraud, R. Thuillier, William Hebrard, M. Petitou, et al.. Organ preservation revisited: anticoagulation rescues borderline kidney grafts. First International Meeting on Ischemia Reperfusion Injuries in Transplantation (IMIRT), Institut National de la Santé et de la Recherche Médicale (INSERM). U1082, IRTOMIT, Poitiers, FRA., May 2012, Poitiers, France. ⟨10.1111/j.1432-2277.2012.01479.x⟩. ⟨hal-02744581⟩
Raphaël Thuillier. New trends for additives to preservation solutions. First International Meeting on Ischemia Reperfusion in Transplantation, 2012, Poitiers, France. ⟨hal-05099542⟩
Raphaël Thuillier. New aspects of cell metabolism during IRI. First International Meeting on Ischemia Reperfusion in Transplantation, 2012, Poitiers, France. ⟨hal-05099535⟩
Raphaël Thuillier, Delphine Dutheil, Vanessa Mallet, - Trieu Minh Tri Ngo, Geraldine Allain, et al.. Hemo2Life (R), a dedicated oxygen carrier, optimizes static kidney preservation. 15. Congress of the ESOT, European Society for Organ Transplantation (ESOT). INT., Sep 2011, Glasgow, United Kingdom. ⟨hal-02749413⟩
Raphaël Thuillier, Geraldine Allain, Benoit Barrou, Henri Leuvenink, Thierry Hauet. Improved short and long term function of DCD kidneys with oxygenated machine perfusion. 15. Congress of the ESOT, European Society for Organ Transplantation (ESOT). INT., Sep 2011, Glasgow, United Kingdom. 387 p., ⟨10.1111/j.1432-2277.2011.01346.x⟩. ⟨hal-02746820⟩
Sébastien Giraud, Raphaël Thuillier, Alexis Puichaud, Alexandre Valagier, Benoit Barrou, et al.. The best peg for organ preservation? A preclinical study. 15. Congress of the ESOT, European Society for Organ Transplantation (ESOT). INT., Sep 2011, Glasgow, United Kingdom. 387 p., ⟨10.1111/j.1432-2277.2011.01349.x⟩. ⟨hal-02746787⟩
Raphaël Thuillier, - Trieu Min Trih Ngo, Sébastien Giraud, Hubert Lathelize, Etienne Marchand, et al.. A therapy to make borderline grafts suitable: curcumin supplementation optimises function recovery and outcome. 15. Congress of the ESOT, European Society for Organ Transplantation (ESOT). INT., Sep 2011, Glasgow, United Kingdom. 387 p. ⟨hal-02747751⟩
Raphaël Thuillier. Curcumin treatment during preservation improves long term graft outcome. The Transplantation Society Congress, 2011, Glasgow (Ecosse), United Kingdom. ⟨hal-05099318⟩
Raphaël Thuillier. HemO2Life, a Dedicated Oxygen Carrier, Optimizes Static Kidney Preservation. The American Transplantation Society Annual Scientific Exchange, 2011, San Antonio, United States. ⟨hal-05099333⟩
Raphaël Thuillier. Ischemia Reperfusion Injury Therapy: Anticoagulant during Preservation Rescues Chronic Kidney Inflammation, Fibrosis and Graft Loss. American Transplant Congress, 2010, San diego, CA, United States. ⟨hal-05099420⟩
Raphaël Thuillier. Anti-thrombin Therapy During Warm Ischemia and Cold Preservation Prevents Chronic Kidney Graft Fibrosis in a NHBD Model. Joint 6th ELITA-ELTR 5th NHBD Meeting, 2010, Londres (Grande Bretagne), United Kingdom. ⟨hal-05099531⟩
Raphaël Thuillier. Diagnosing ischemia reperfusion injury: analysis of severity markers in a pig model of kidney transplantation. The Transplantation Society Congress, 2010, Vancouver (BC), Canada. ⟨hal-05099314⟩
Raphaël Thuillier. A Way to Better Grafts: Curcumin Supplementation Improves Graft Outcome.. European Society Of Transplantation Congress, 2010, San diego, CA, United States. ⟨hal-05099426⟩
Raphaël Thuillier. Diagnosing Ischemia Reperfusion Injury: Analysis of Severity Markers in a Pig Model of Kidney Transplantation. American Transplant Congress, 2010, San diego, CA, United States. ⟨hal-05099416⟩
Raphaël Thuillier. Oxygenated Machine Perfusion of DCD Kidneys: towards further reducing DGF and improving graft quality. Joint 6th ELITA-ELTR 5th NHBD Meeting, 2010, London, United Kingdom. ⟨hal-05099299⟩
Raphaël Thuillier. Improving Kidney Preservation: Marine Worm Hemoglobin Supplementation Rescues Ischemia Reperfusion Injury.. American Transplant Congress, 2010, San diego, CA, United States. ⟨hal-05099422⟩
Raphaël Thuillier. Improving kidney preservation: HEMO2Life® supplementation rescues ischemia reperfusion injury. The Transplantation Society Congress, 2010, Vancouver (BC), Canada. ⟨hal-05099303⟩
Raphaël Thuillier. Ischemia reperfusion injury therapy: inhibitor of coagulation during preservation rescues chronic kidney inflammation, fibrosis and graft loss. The Transplantation Society Congress, 2010, Vancouver (BC), Canada. ⟨hal-05099308⟩
Raphaël Thuillier. Are Bmp7 and Hsp70 early markers of chronic kidney graft function ? Proteomic and genomic analysis of Ischemia Reperfusion Injury. European Society Of Transplantation Congress, 2009, Paris, France. ⟨hal-05099385⟩
Raphaël Thuillier. Look Inside the Machine: Mechanistic Analysis of the Benefits of Machine Perfusion On Non Beating Heart Donors Grafts. American Transplant Congress, 2009, Boston (MA), United States. ⟨hal-05099286⟩
Raphaël Thuillier. Comparative analysis of warm and cold ischemia : early Hsp70 expression is associated with better outcome in kidney grafts. World Congress of Nephrology, 2009, Milan (Italie), Italy. ⟨hal-05099372⟩
Raphaël Thuillier. The weak spot of Ischemia Reperfusion Injury: Thrombin inhibition rescues chronic kidney inflammation and fibrosis.. European Society Of Transplantation Congress, 2009, Paris, France. ⟨hal-05099290⟩
Raphaël Thuillier. Hit Coagulation and the Ischemic Injury Will Fall: Protective Effect of Thrombin Inhibition Against Chronic Kidney Graft Inflammation and Tubular Atrophy. American Transplant Congress, 2009, Boston (MA), United States. ⟨hal-05099364⟩
Raphaël Thuillier. The answer is in machine perfusion: analysis of machine perfusion on donor after cardiac arrest.. European Society Of Transplantation Congress, 2009, Paris, France. ⟨hal-05099387⟩
Raphaël Thuillier. The story of polyethylene glycol part 1: PEG during cold preservation preserves grafts function.. European Society Of Transplantation Congress, 2009, Paris, France. ⟨hal-05099405⟩
Raphaël Thuillier. Is coagulation the key to ischemia reperfusion injury treatment? Thrombin inhibition rescues chronic kidney fibrosis in autologous kidney transplantation model. World Congress of Nephrology, 2009, Milan (Italie), Italy. ⟨hal-05099376⟩
Raphaël Thuillier. Improving DCAD grafts: direct thrombin inhibition prevents delayed graft function and acute injury.. European Society Of Transplantation Congress, 2009, Paris, France. ⟨hal-05099394⟩
Raphaël Thuillier. Understand the machine: mechanistic analysis of the benefits of machine perfusion on diseased after cardiac arrest donors grafts. World Congress of Nephrology, 2009, Milan (Italie), Italy. ⟨hal-05099384⟩
Raphaël Thuillier. Immunologic camouflage and extracellular composition protects against ischemia reperfusion injury and allograft fibrosis.. European Society Of Transplantation Congress, 2009, Paris, France. ⟨hal-05099295⟩
Raphaël Thuillier. Comparative analysis of IGL1 and MPS in machine perfusion, a Waters RM3 study.. Comparative analysis of IGL1 and MPS in machine perfusion, a Waters RM3 study., 2009, Paris, France. ⟨hal-05099413⟩
Raphaël Thuillier. The story of polyethylene glycol part 2: PEG during cold preservation protects against chronic graft fibrosis.. European Society Of Transplantation Congress, 2009, Paris, France. ⟨hal-05099408⟩
Raphaël Thuillier. Coagulation in kidney graft ischemia reperfusion injury: protective effect of thrombin inhibition against chronic kidney graft inflammation and tubular atrophy. World Congress of Nephrology, 2009, Milan (Italie), Italy. ⟨hal-05099368⟩
Raphaël Thuillier. Under a Mac Attack: Macrophages are an Important Agent of Fibrosis in Human Kidney Allografts.. American Transplant Congress, 2008, Toronto, Canada. ⟨hal-05099279⟩
Raphaël Thuillier. Is Coagulation the Achilles’ Heel of Ischemia Reperfusion Injury ? Thrombin Inhibition Rescues Chronic Kidney Fibrosis. European Society for Organ Transplantation Basic Science Symposium, 2008, Brussels, Belgium. ⟨hal-05099285⟩
Raphaël Thuillier. Big Mac Uncovered: Macrophage Induced Epithelial-Mesenchymal Transformation (EMT) Contributes to Late Kidney Allograft Failure. American Transplant Congress, 2007, San Francisco CA, United States. ⟨hal-05099265⟩
Raphaël Thuillier. Macrophage Induced Epithelial-Mesenchymal Transformation (EMT) Contributes to Late Kidney Allograft Failure.. Basic Science Symposium of The Transplantation Society, 2007, Halifax, Canada. ⟨hal-05099273⟩
Raphaël Thuillier. Big mac attack? Defining the role of IL-13 and macrophage activation in the pathogenesis of chronic allograft nephropathy.. World Transplant Congress, 2006, Boston (MA), United States. ⟨hal-05097933⟩

Brevet (4 documents)

Raphaël Thuillier. Use of algorithms for predicting survival of a patient treated with extracorporeal membrane oxygenation. France, Patent n° : 20315122.0. 2019. ⟨hal-05099594⟩
Raphaël Thuillier. Methods and compositions for the preservation of organs. France, Patent n° : EP16306017.1. 2018. ⟨hal-05099590⟩
Raphaël Thuillier. Composés permettant la conservation de cellules, tissus et organes, compositions et utilisations. France, Patent n° : 14 59490. 2015. ⟨hal-05099584⟩
Raphaël Thuillier. Oligosaccharide conjugates in the prevention of ischemia-reperfusion injury. France, Patent n° : WO2012146774A1. 2012. ⟨hal-05099583⟩

Poster (1 document)

A. Amiri, R. Thuillier, L. Badet, Pierre Couturier, William Hebrard, et al.. Analysis of dose-effect of HEMARINA-M101 in a porcine autotransplanted and perfused kidney model. 3. International Meeting on Ischemia Reperfusion Injury (IMIRT), Apr 2016, Poitiers, France. Wiley-Blackwell, Transplant International, 29, 1 p., 2016. ⟨hal-02744004⟩

Chapitre d'ouvrage (2 documents)

Raphaël Thuillier, Thierry Hauet, Frédéric Favreau. Ischemie reperfusion : Concepts.. La Transplantation Rénale, 2011, 2257204182. ⟨hal-05099443⟩
Raphaël Thuillier, Mannon B Rose. The immunology of chronic allograft injury in Chronic Allograft Failure: Natural History, Pathogenesis, Diagnosis and Management.. The immunology of chronic allograft injury in Chronic Allograft Failure: Natural History, Pathogenesis, Diagnosis and Management., 2007. ⟨hal-05099453⟩

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