• Maitre de conférences en Biologie de la cellule et des molécules
  • Université de Poitiers
    LITEC
  • Mots-clés : Inflammation, Cytokines, Peau, Modèles cellulaires peau, Modèles animaux d'inflammation cutanée.

Publications HAL

  • Dominique Heymann, Frédéric Lézot, Javier Muñoz-Garcia, Jorge William Vargas-Franco, Kristina Schiavone, et al.. Interleukin-34 orchestrates bone formation through its binding to Bone Morphogenic Proteins. Theranostics, In press, ⟨10.7150/thno.107340⟩. ⟨hal-04901466⟩
  • Ivana Gabriela Reidel, Cecilia Carol Curti, Léa Dorémus, Emile Béré, Adriana Delwail, et al.. Liposomal co-encapsulation of a novel gemini lipopeptide and a CpG-ODN induces a strong Th1 response with the co-activation of a Th2/Th17 profile and high antibody levels. Vaccine, 2024, ⟨10.1016/j.vaccine.2024.02.011⟩. ⟨hal-04490420⟩
  • Magali Croquette, Alicia Faugeroux, Clémence Fonlupt, Julie Godet, Éric Frouin, et al.. Interleukin 34 exerts anti-inflammatory activities on keratinocytes and is down-regulated in psoriatic-inflamed skin. Journal of Investigative Dermatology, 2023, ⟨10.1016/j.jid.2023.05.023⟩. ⟨hal-04133828⟩
  • Valérie Coronas, Patricia Arnault, Jean-François Jégou, Laetitia Cousin, Hanitriniaina Rabeony, et al.. IL-22 Promotes Neural Stem Cell Self-Renewal in the Adult Brain. STEM CELLS, 2023, 41 (3), pp.252-259. ⟨10.1093/stmcls/sxad003⟩. ⟨hal-04003042⟩
  • Guillaume Larid, Adriana Delwail, Thomas Dalle, Philippe Vasseur, Christine Silvain, et al.. Ex vivo cytokine production in psoriatic disease: Towards specific signatures in cutaneous psoriasis and peripheral psoriatic arthritis. Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.993363⟩. ⟨hal-03894861⟩
  • Florent Carsuzaa, Émilie Béquignon, Matthieu Bainaud, Jean-François Jégou, Xavier Dufour, et al.. Oncostatin M Counteracts the Fibrotic Effects of TGF-β1 and IL-4 on Nasal-Polyp-Derived Fibroblasts: A Control of Fibrosis in Chronic Rhinosinusitis with Nasal Polyps?. International Journal of Molecular Sciences, 2022, 23 (11), pp.6308. ⟨10.3390/ijms23116308⟩. ⟨hal-03801056⟩
  • Sevda Cordier-Dirikoc, Nathalie Pedretti, Julien Garnier, Sandrine Clarhaut-Charreau, Bernhard Ryffel, et al.. Dermal fibroblasts are the key sensors of aseptic skin inflammation through interleukin 1 release by lesioned keratinocytes. Frontiers in Immunology, 2022, 13, pp.984045. ⟨10.3389/fimmu.2022.984045⟩. ⟨hal-03801039⟩
  • Jean-Claude Lecron, Sandrine Clarhaut-Charreau, Laure Favot-Laforge, Jean-François Jégou, Charles Bodet, et al.. IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin. Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.984016⟩. ⟨hal-04185385⟩
  • Philippe Vasseur, Mathilde Pohin, Coralie Gisclard, Jean‐François Jégou, Franck Morel, et al.. Chronic Alcohol Consumption Exacerbates the Severity of Psoriasiform Dermatitis in Mice. Alcoholism: Clinical and Experimental Research, 2020, 44 (9), pp.1728-1733. ⟨10.1111/acer.14400⟩. ⟨hal-03797226⟩
  • Taoufik El Kabir, Benjamin Bringier, Majdi Khoudeir, Franck Morel, Jean-Claude Lecron, et al.. Photometric computer vision-aided system for psoriasis severity scoring: a preclinical study based on a mouse model of psoriasis. Journal of Electronic Imaging, 2020, 29 (04), pp.1. ⟨10.1117/1.JEI.29.4.041003⟩. ⟨hal-02516809⟩
  • Alexandre Crépin, Jean-Francois Jégou, Sonia André, Florine Ecale, Anastasia Croitoru, et al.. In vitro and intracellular activities of frog skin temporins against Legionella pneumophila and its eukaryotic hosts. Scientific Reports, 2020, 10 (1), pp.3978. ⟨10.1038/s41598-020-60829-2⟩. ⟨hal-02505077⟩
  • Vincent Huguier, Jean-Philippe Giot, Marie Simonneau, Pierre Levillain, Sandrine Charreau, et al.. Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFβ1 on fibrosis markers. Scientific Reports, 2019, 9 (1), pp.2113. ⟨10.1038/s41598-019-38572-0⟩. ⟨hal-04184816⟩
  • Marie Simonneau, Eric Frouin, Vincent Huguier, Cynthia Jermidi, Jean François Jégou, et al.. Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression. Oncotarget, 2018, 9 (92), pp.36457-36473. ⟨10.18632/oncotarget.26355⟩. ⟨hal-04186396⟩
  • Mathilde Pohin, Carolina Veaute, Julien Garnier, Christine Barrault, Laure Cronier, et al.. Development of a new model of reconstituted mouse epidermis and characterization of its response to proinflammatory cytokines. Journal of Tissue Engineering and Regenerative Medicine, 2018, 12, pp.e1098- e1107. ⟨10.1002/term.2442⟩. ⟨hal-01699562⟩
  • Julie Cremniter, Charles Bodet, David Tougeron, Xavier Dray, Joëlle Guilhot, et al.. Th-17 response and antimicrobial peptide expression are uniformly expressed in gastric mucosa of Helicobacter pylori -infected patients independently of their clinical outcomes. Helicobacter, 2018, 23, pp.e12479. ⟨10.1111/hel.12479⟩. ⟨hal-01780541⟩
  • P. Vasseur, M. Pohin, Jf. Jégou, L. Favot, N. Venisse, et al.. Liver fibrosis is associated with cutaneous inflammation in the imiquimod-induced murine model of psoriasiform dermatitis. British Journal of Dermatology, 2018, 179, pp.101-109. ⟨10.1111/bjd.16137⟩. ⟨hal-01699551⟩
  • Amandine Buffière-Morgado, Elodie Couderc, Adriana Delwail, Laure Favot, Jean-François Jégou, et al.. Characterization of skin Th17 transcriptional profiles in psoriatic patients under adalimumab biotherapy. European Journal of Dermatology, 2017, ⟨10.1684/ejd.2017.3127⟩. ⟨hal-01705097⟩
  • Geraldine Gourru-Lesimple, Cyrille Mathieu, Thomas Thevenet, Vanessa Guillaume-Vasselin, Jean-François Jégou, et al.. Measles virus infection of human keratinocytes: Possible link between measles and atopic dermatitis. Journal of Dermatological Science, 2017, 86 (2), pp.97-105. ⟨10.1016/j.jdermsci.2017.01.015⟩. ⟨hal-01911528⟩
  • Elodie Couderc, Franck Morel, Pierre Levillain, Amandine Buffière-Morgado, Magalie Camus, et al.. Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis. PLoS ONE, 2017, 12 (7), pp.e0181486. ⟨10.1371/journal.pone.0181486⟩. ⟨hal-01703911⟩
  • Mathilde Pohin, William Guesdon, Andela Andrine Mekouo, Hanitriniaina Rabeony, Isabelle Petit-Paris, et al.. Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation. European Journal of Immunology, 2016, 46 (7), pp.1737 - 1751. ⟨10.1002/eji.201546216⟩. ⟨inserm-01701320⟩
  • Philippe Vasseur, Laura Serres, Jean-Francois Jegou, Mathilde Pohin, Adriana Delwail, et al.. High-Fat Diet-Induced IL-17A Exacerbates Psoriasiform Dermatitis in a Mouse Model of Steatohepatitis. American Journal of Pathology, 2016, 186 (9), pp.2292--2301. ⟨10.1016/j.ajpath.2016.05.012⟩. ⟨hal-01390977⟩
  • J.-C. Lecron, P. Vasseur, L. Serres, J.-F. Jégou, M. Pohin, et al.. IL-17A EXACERBATES PSORIASIFORM DERMATITIS IN A MOUSE MODEL OF HIGH-FAT DIET-INDUCED STEATOHEPATITIS. Cytokine, 2016, 87, pp.51--51. ⟨10.1016/j.cyto.2016.07.020⟩. ⟨hal-01485264⟩
  • Hanitriniaina Rabeony, Mathilde Pohin, Philippe Vasseur, Isabelle Petit-Paris, Jean-François Jégou, et al.. IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome. European Journal of Immunology, 2015, 45 (10), pp.2847 - 2857. ⟨10.1002/eji.201445215⟩. ⟨hal-01702889⟩
  • Hanitriniaina Rabeony, Isabelle Petit-Paris, Julien Garnier, Christine Barrault, Nathalie Pedretti, et al.. Inhibition of Keratinocyte Differentiation by the Synergistic Effect of IL-17A, IL-22, IL-1α, TNFα and Oncostatin M. PLoS ONE, 2014, 9 (7), ⟨10.1371/journal.pone.0101937⟩. ⟨hal-01703025⟩
  • Joséphine M. Reynaud, Jean-François Jégou, Jérémy C. Welsch, Branka Horvat. Human herpesvirus 6A infection in CD46 transgenic mice: viral persistence in the brain and increased production of proinflammatory chemokines via Toll-like receptor 9. Journal of Virology, 2014, 88 (10), pp.5421-5436. ⟨10.1128/JVI.03763-13⟩. ⟨hal-01911356⟩
  • Jean-François Jégou, Philippe Chan, Marie-Thérèse Schouft, Philippe Gasque, Hubert Vaudry, et al.. Protective DNA vaccination against myelin oligodendrocyte glycoprotein is overcome by C3d in experimental autoimmune encephalomyelitis. Molecular Immunology, 2007, 44 (15), pp.3691-3701. ⟨10.1016/j.molimm.2007.04.008⟩. ⟨hal-04038688⟩
  • Jean-François Jégou, Philippe Chan, Marie-Thérèse Schouft, Mark Griffiths, James Neal, et al.. C3d Binding to the Myelin Oligodendrocyte Glycoprotein Results in an Exacerbated Experimental Autoimmune Encephalomyelitis. Journal of Immunology, 2007, 178 (5), pp.3323-3331. ⟨10.4049/jimmunol.178.5.3323⟩. ⟨hal-04038686⟩
  • E. Fraillon, N. Lebonvallet, J. Lecron, Jean-François Jégou, F. Morel, et al.. 335 Exploring the role of the TRPV3 calcium channel in psoriasis. 53rd Annual ESDR Meeting, Sep 2024, Lisbon (Portugal), Portugal. pp.S286, ⟨10.1016/j.jid.2024.10.344⟩. ⟨hal-04868108⟩
  • M. Croquette, A. Faugeroux, C. Fonlupt, F. Broca, M. Martin, et al.. 310 Interleukin-34 expression and regulatory role in healthy skin and in inflamed skin during psoriasis and systemic sclerosis. 53rd Annual ESDR Meeting, Sep 2024, Lisbon (Portugal), Portugal. pp.S282, ⟨10.1016/j.jid.2024.10.319⟩. ⟨hal-04868088⟩
  • Sevda Cordier-Dirikoc, Nathalie Pedretti, Julien Garnier, Sandrine Clarhaut-Charreau, Bernhard Ryffel, et al.. Dermal fibroblasts are important relay cells in skin inflammation, highly sensitive to interleukin 1 released by lesioned keratinocytes. Cosm'Innov 5th edition 2023 : The international congress for cosmetics research, Cosmetic Valley, May 2023, Orléans, France. pp.1-61, ⟨10.1111/ics.12921⟩. ⟨hal-04501621⟩
  • M. Croquette, C. Fonlupt, A. Faugeroux, J. Godet, E. Frouin, et al.. 216 Downregulation of interleukin-34 in psoriatic lesions and potential immunoregulatory role in skin inflammation. 50th ESDR Annual Meeting, European Society for Dermatological Research, Sep 2021, Virtual congress, France. pp.S186, ⟨10.1016/j.jid.2021.08.221⟩. ⟨hal-05007915⟩
  • Magali Croquette, Clémence Fonlupt, Alicia Faugeroux, Julie Godet, Éric Frouin, et al.. Interleukin-34 expression by keratinocytes is downregulated in inflamed psoriatic skin lesions: toward an immunoregulatory role in skin inflammation.. 6 th European Congress of Immunology, 1–4 September 2021, Virtual meeting, Sep 2021, Virtual congress, France. pp.1-448, ⟨10.1002/eji.202170200⟩. ⟨hal-05007949⟩
  • Taoufik El Kabir, Benjamin Bringier, Majdi Khoudeir, Jean Claude Lecron, Franck Morel, et al.. Non invasive control and scoring of psoriasis severity. Fifteenth International Conference on Quality Control by Artificial Vision, May 2019, Mulhouse, France. pp.14, ⟨10.1117/12.2520690⟩. ⟨hal-02374311⟩
  • Taoufik El Kabir, Benjamin Bringier, Majdi Khoudeir, Jean-François Jégou, Jean Claude Lecron, et al.. Diagnostic du psoriasis par vision par ordinateur. Symposium en Recherche sur l’inflammation et la Cancérologie Dermatologiques en Nouvelle Aquitaine, Nov 2018, Poitiers, France. ⟨hal-02374370⟩
  • Taoufik El Kabir, Benjamin Bringier, Majdi Khoudeir, Jean François Jegou, Jean Claude Lecron, et al.. Diagnostic du psoriasis par la stéréo photométrie. Journées Imagerie Optique Non-Conventionnelle 2018, Mar 2018, Paris, France. ⟨hal-02374383⟩
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